Tampa Bay Buccaneers vs. LA Rams Prediction & Betting Picks (November 23, 2025)
We get a good one on Sunday Night Football in week 12, where the Los Angeles Rams will host the Tampa Bay Buccaneers as near-touchdown favorites (-7).
Both teams have a ton to play for, as they are in first place in their respective divisions. The battle for the #1 seed in the NFC is alive and well, too. L.A. is presently tied with the Eagles, but an upset win by the Buccaneers would open this race up.
Tampa Bay has the Carolina Panthers breathing down their neck in the NFC South, but solid play and a respectable 4-2 road record makes them a viable underdog pick. This game also sports a healthy 49.5 total, meaning we’re in for a fun scoring environment no matter the outcome.
But what’s the best bet for the Buccaneers vs. Rams clash? There are a few that stand out, but I’ll break down the latest odds and key matchups to find the top plays. Read on for my preferred picks and ultimate Buccaneers vs. Rams prediction.
Game Info Snapshot
- Date & Location: Sunday, November 23rd, 2025 | Kickoff at 7:20 pm ET (NBC) at SoFi Stadium in Inglewood, CA
- Team records entering the game:
- Buccaneers: 6-4
- Rams: 8-2
- Odds (from FanDuel)
- Spread: Buccaneers +7 (-110) | Rams -7 (-110)
- Moneyline: Buccaneers (+300) | Rams (-375)
- Total: Over 49.5 (-110) | Under 49.5 (-110)
This game’s pricing indicates a sizable gap between the Bucs and Rams, not to mention a noted edge for Los Angeles at home. The oddsmakers could also be factoring the cross-country travel for the Buccaneers, not to mention the primetime setting.
Despite the big spread, this is a nice game total, which suggests we should be in for a fair amount of scoring. Both offenses are also plenty capable, which further plays into this line.
Buccaneers vs. Rams Storylines to Watch
There are several storylines to watch for this big NFC tilt on Sunday Night Football. The biggest has to be whether the Rams can exert further dominance and distance themselves as the best team in this conference.
L.A. has certainly looked the part of a legit title threat, but winning home games where they are reasonable favorites tends to be the mark of a champion.
Here are some more Rams vs. Buccaneers storylines to keep in mind:
- Banged Up: As if the Buccaneers weren’t going to be challenged enough against a loaded Rams offense, they’ll be without stud defensive back Jamel Dean, among others. Dean’s absence could be felt for a defense that leans heavily on forcing turnovers (1.6 per game).
- Turnover Battle: If Tampa Bay’s defense is going to lose out on some playmaking, they may need to make sure they take extra good care of the football. They do that at a high level (4th fewest giveaways), but the Rams (7th fewest) aren’t far behind.
- Healthy Returns: The Buccaneers are banged up on defense, but they might get reinforcements on offense. Both Chris Godwin and Bucky Irving practiced in limited fashion this week and have yet to be ruled out for Sunday Night Football.
Team Profiles
Tampa Bay Buccaneers
The Buccaneers have been rock solid all year, as they got off to a nice 3-0 start, and have held strong to a respectable 6-4 record.
Injuries have begun to catch up with the Bucs, as they got smoked by the Bills last week, and have lost three of their last four.
On the year, this is a dynamic offensive team when at full strength. Here’s a quick look where they’ve stood out in key areas so far:
- Pass Happy: The Bucs have a capable rushing attack, but it’s been banged up for a while now. They tend to pass a lot more than they run (57% pass rate), and it’s kept them among the better offenses (15th in passing and 17th in yards per pass) through the air.
- Max Protect: Tampa Bay does a fantastic job at both protecting quarterback Baker Mayfield and limiting turnovers. The Bucs have the 10th lowest sack rate, while Mayfield has his squad ranking 3rd with one of the lowest interception rates (0.88%).
- Stiff Front: The Bucs have weakened in this regard in recent weeks, but on the year they’ve been a tough defense to run on. Their yards per rush allowed are at the league average (4.2), but they come into week 12th ranked 10th in rushing yards allowed per game.
Los Angeles Rams
Los Angeles also got off to a nice start early in the year, as they started 2-0 and never really looked back. They did lose to the Eagles in a tight 26-33 game in week three, while their other loss is a three-point defeat by the hands of the NFC West rival 49ers.
That loss to Philly is key, as the Eagles are also 8-2 and own the tiebreaker. The Rams need to keep pace and hope they end the regular season with the better record if they want the #1 seed in the NFC.
Overall, this has been an extremely balanced team that ranks inside the top-10 in scoring both offensively and defensively. Matthew Stafford is also piecing together a legit NFL MVP caliber campaign.
Here’s how the Rams have stood out on the year:
- Unstoppable: The Rams are not an easy team to get rid of. If you hold them to fourth down, they can still kill you at an elite rate (4th best conversion rate) and they tend to finish the job (7th) when they get inside the 20.
- Pass Centric: L.A. has excelled in every way through the air. Stafford has been ablaze, putting up 27 passing scores to just two interceptions. The Rams rank inside the top-10 in yards per pass, sack rate, interception rate, and passing yards per game. They throw almost 57% of the time and everyone knows it – yet nobody can consistently stop them.
- Stingy Front: The Rams do a fantastic job against the run on a per carry basis. Overall volume works against them slightly, but they still own the league’s 11th best run defense and are only allowing 3.9 yards per rush (6th).
Key Buccaneers vs. Rams Matchups & Angles
Check out the key Rams vs. Buccaneers vs. matchups:
- Rams passing offense vs. Buccaneers secondary: Jamel Dean hurts the Bucs a lot here. Tampa Bay does force a good amount of turnovers, but their 21st ranked pass defense will absolutely need to be active in that area to have success in this matchup.
- Buccaneers rush offense vs. Rams run defense: Even if the Bucs get Bucky Irving back, it’s unknown how much he’ll be limited. How successful he can be – or how much the Bucs even try to run – against a stingy L.A. defensive line is a key matchup to consider.
- Can Anyone Stop Puka Nacua?: The Rams have two elite wide receivers in Puka Nacua and Davante Adams, but without a key defensive back, I’m not sure the Bucs will slow down either of them. That could especially mean big things for Puka, who has 7+ catches in seven different games this season.
Betting Trends & Odds Context
Take a look at the latest Buccaneers vs. Rams odds, per FanDuel:
| Team | Spread | Moneyline | Total |
|---|---|---|---|
Buccaneers | +7 (-110) | +300 | Over 49.5 (-115) |
Rams | -7 (-110) | -375 | Under 49.5 (-105) |
Take a look at some key betting trends for this showdown:
- Public Betting: All the action is favoring the Rams right now. L.A. is getting 87% of the bets and 873% of the money.
- Record History: These two sides have only played each other 29 times, with the Rams holding a commanding 19-10 series edge. The Bucs won the last meeting (16-13) in 2022, but L.A. has claimed three of the last four games.
- ATS Tidbits: Tampa Bay is just 5-5 against the spread, but they’re 4-2 ATS on the road and 3-3 ATS as the underdog. The Rams have been great (7-3) against the spread and are 3-2 ATS at home and 7-2 against the spread when favored.
Best Bets for Rams vs. Buccaneers
Pick 1: Buccaneers ATS +7 (-110) – 7/10 Confidence
Why We Like It
My favorite Buccaneers vs. Rams pick is for the Bucs to beat this big spread. Tampa Bay has been solid on the road, could be getting some key players back, and have a lot to play for. This is also a pretty big spread in a game that could easily go down to the wire.
Risks/What to Watch
The Rams have been pretty dominant ATS, are at home, and grade out as the better team across the board. They have won by 7+ in six different games, so blowing teams out isn’t abnormal for them.
Pick 2: Over 49.5 (-110) – 7/10 Confidence
Why We Like It
Tampa Bay’s defensive bite is lessened by injuries. I think they can keep this close, but shutting down a dynamic Rams offense that puts up 27.2 points per game seems unlikely. The Bucs are plenty capable (25.2 points per game) of showing up in a tight shootout.
Risks/What to Watch
Los Angeles has the far better defense and they’re at home with just as much to play for. They own the NFL’s second best scoring defense, which could negatively impact things for Over bettors.
Pick 3: Prop Play – Puka Nacua Over 7.5 Receptions (+106) – 7/10 Confidence
Why We Like It
Puka Nacua seems to get at least seven grabs almost by default. He has several other games where he has 10+ as well. He’s been on the quiet side in recent weeks, but this matchup sets up pretty well for the L.A. passing game. I can see him smashing this nice plus money prop.
Risks/What to Watch
Los Angeles is loaded and dynamic. It could always turn into a Kyren Williams or Davante Adams game. A blowout would negate the necessity of passing a lot or force-feeding Nacua, too.
Odds lines for Buccaneers vs. Rams continue shifting as bettors react to injuries and late-week action—track changes closely and compare them at our top football betting sites.
Final Verdict: Rams Stay in Play for the #1 Seed
I think we’ll get these teams about right where we expect in terms of production and scoring. L.A.’s stiff run defense may not have a huge hold on the Bucs due to their tendency to air it out, while the Bucs are going to be too banged up on defense to slow down Matthew Stafford.
That should equate to a Rams home win, but Baker Mayfield and co. have enough weaponry to keep this one interesting. That should lead to the Buccaneers beating this 7-point spread, and if both teams can hover around their scoring averages, we can see the Over deliver as well.
Ultimately, home field edge, talent, and matchups all favor the Rams. There isn’t much value in betting on L.A.’s ML, though, so we should take advantage of these other bets.
Final Score Prediction: Rams 27, Buccaneers 24
