Cleveland Guardians vs. New York Yankees Prediction (June 5, 2025)
Welp, the Yankees went down 4-0 in the Bronx—their home turf. Oof. The Guardians scored 3 runs in the first inning, so their rotation was working tonight as opposed to the previous games against NY. As for the Yankees? They got their first extra-base hit in the bottom of the ninth inning. What a difference a night makes!
It’s tied up 3-3, and we all want to see what happens next at Yankee Stadium in the next matchup. The Yanks want to stop at the top of the AL East, and Cleveland wants to get a better footing in the league.
Will pitchers Max Fried vs. Slade Cecconi make a difference in the next game? Keep reading to find out what the odds and trends are and for our picks for the best bets!
Game Snapshot
- Matchup: Cleveland Guardians (33–27) vs. New York Yankees (37–23)
- Date & Time: Thursday, June 5, at 7:05 pm ET
- Venue: Yankee Stadium, Bronx, NY
- Broadcast: YES Network
- Weather: Clear skies with a temperature around 73°F
Prediction Breakdown
38.2%
61.8%
According to GamblingSite.com
Pitching Matchup
The Yankees and Guardians will close out their three-game set Thursday night in the Bronx. New York is sending Max Fried to the mound—they don’t want a repeat of the last game. Cleveland counters with Slade Cecconi, who’s trying to find his place in the rotation. Here’s how these two throwers compare!
Yankees: Max Fried (7-1, 1.92 ERA)
Fried’s been one of the most reliable arms in the league this year. He’s killed it at Yankee Stadium with an ERA under 2.00 and has held hitters to minimal damage all season. He is coming off a rare misstep against the Dodgers, where he gave up six runs, but there’s no indication of a bigger issue.
Guardians: Slade Cecconi (1-1, 5.28 ERA)
Cecconi hasn’t quite settled in since being moved into the rotation. He gave up five runs in four innings his last time out and has already allowed five home runs in only three starts. His fastball has been meh, and command issues have put him in bad spots early in counts. Against a deep Yankees lineup? He’s a risk.
Team Form & Trends
The Yankees have been solid at home. The Guardians have been anything but while on the road.
| Yankees | Guardians |
|---|---|
– 37-23 overall, 1st in AL East | – 33-27 overall, 3rd in AL Central |
Key Player Spotlight
Below are the hitters that will most likely impact Thursday’s game.
Yankees: Aaron Judge
- Slashed .364/.453/.798 with 11 home runs in May
- Tough matchup for any right-hander, including Cecconi
- Leads the team in hitting and extra-base hits
Guardians: José Ramírez
- Team leader in RBIs and total bases
- Brings power from both sides of the plate
- Needs to produce if Cleveland’s going to break through against Fried
Latest Betting Odds
Below are the latest odds from DraftKings and we think there is some value to be found.
| Team | Run Line | Moneyline | Total Runs |
|---|---|---|---|
Guardians | +1.5 (+105) | +215 | Over 8.5 (-120) |
Yankees | -1.5 (-125) | -265 | Under 8.5 (+100) |
Best Bets
Here’s where we think the smart money is if you’re betting on this one!
- Yankees -1.5 (-125) | With Fried on the mound and a deeper lineup? The Yankees are in a really good spot to cover a multi-run spread.
- Under 8.5 Runs (+100) | Fried has kept scoring in check all season long, and Cleveland hasn’t generated much offense on the road. A lower total feels right..
- Yankees First 5 Innings (F5) Run Line -0.5 (-110) | Fried controls games in early innings, and the Guardians have been really slow to start. Backing New York through five innings makes sense in this spot.
Closing Pitch: Yankees Look to Dominate
Max Fried gives the Yankees an advantage in the series finale. He’s been hard to hit at home, and Slade Cecconi has had some issues keeping the ball in the park. The Yankees have hit well in the Bronx, and the Guardians haven’t done much of anything on the road.
Top Betting Picks
- Yankees -1.5 (+105)
- Under 8.5 (-110)
- Yankees First 5 Innings -0.5 (-110)
Fried’s form, paired with home-field advantage and a stronger top-to-bottom batting order, makes the Yankees the safer side to back in this one.
Final Score Prediction: Yankees 5, Guardians 2
New York has the better starter, has a more reliable offense at home, and a bullpen that handles late-game spots really well. Fried should keep Cleveland in check while the Yankees do enough to pull away.
Be cautious with over bets! Both teams have shown they can limit scoring, so if you’re targeting any of these lines, it’s always wise to act early before the odds move closer to the first pitch!
Check the latest odds at your preferred sportsbook before betting. And as always—wager responsibly and never risk more than you can afford to lose.
