Diamondbacks vs. Dodgers MLB Prediction & Best Bets (May 19, 2025)

It’ll be a relatively cool Monday night in Los Angeles, and that means the ball will carry and the fans will show up sometime around the third or fourth inning. The Dodgers are trying to stay on top of the division without totally burning out their pitching staff. Arizona’s trying to rain on their parade, and they’ve got the dude on the mound who did that already.
There are two starters with very different résumés, two lineups that don’t need much help putting up crooked numbers, and just enough tension to make the dugouts twitchy. It could be a pitcher’s duel. It could also be four hours long with eleven pitching changes.
That’s baseball. It’ll be a good game or a fun mess. Either way, let’s see what’s happening with the Diamondbacks vs. the Dodgers.
Quick Hit: Why This Game Matters
What’s riding on this game? Um, just a little bit of everything.
- Division Pressure: The Dodgers are trying not to give Arizona any daylight in the standings.
- Arizona’s Window: The Diamondbacks are hovering close enough to matter and need series wins like this to stay in the playoff picture conversation.
- Power vs. Power: Both teams bring the bats, and we’ve seen recent matchups between them turn into track meets on the scoreboard.
- Momentum Swing: A win here is a tone-setter for the rest of the series, and quite possibly the next few weeks.
- Night Game Spotlight: Prime time, big market, and a national broadcast mean there’ll be a lot more eyes on every pitch.
Game Snapshot
- Matchup: Arizona Diamondbacks (25-22) vs. Los Angeles Dodgers (29-18)
- Date & Time: Monday, May 19, 2025, at 10:10 pm ET
- Venue: Dodger Stadium, Los Angeles, CA
- Broadcast: MLB Network, SportsNet LA
- Weather: 74°F, clear skies, light wind
Who’s Pitching?
There are two righties on the mound. Pfaadt knows how to handle the lineup, and he’s got receipts. Knack looks like he’s still in the trying-to-figure-it-out phase.
Arizona Diamondbacks: Brandon Pfaadt (RHP)
Pfaadt’s been Arizona’s most reliable starter throughout the early season. His control’s been a little spotty at times, but when he’s dialed in? Hoo boy, he mixes speeds and knows how to work both sides of the plate. His last start wasn’t pretty, but he’s already butchered the Dodgers once this year, and that counts.

- Season stats: 6–3, 3.73 ERA, 1.30 WHIP, 50.2 IP, 44 K, 13 BB
- Last start: 4 ER in 4 IP vs. San Francisco
- Previous outing vs. Dodgers: 6.1 scoreless innings, 4 H, 0 BB, 6 K
Los Angeles Dodgers: Landon Knack (RHP)
Knack’s still trying to prove himself, and he’s shown flashes of brilliant pitching. But he’s inconsistent, which makes his starts something of a “What’s gonna happen here?” Arizona’s already touched him up once, and his numbers look like he could be vulnerable here.

- Season stats: 2–1, 5.89 ERA, 1.53 WHIP, 18.1 IP, 20 K, 8 BB
- Last start: 5 ER in 4.2 IP vs. Oakland
- Career vs. Arizona: 0–1, 4.82 ERA in two starts
Key Players to Watch
Who could make a difference in this game? There are a few to watch. One big whiff or a big connect could swing the game, but so could a defensive misstep.
Arizona Diamondbacks

- Ketel Marte: Slugging .545 in his last 10 games and already has 3 bombs vs. L.A. this season.
- Eugenio Suárez: Leads his team with 14 home runs and has been hitting mistake pitches out with authority.
- Gabriel Moreno: He’s been steady behind the plate and productive at it, hitting .253 while handling a rotating pitching staff.
Los Angeles Dodgers

- Freddie Freeman: The definition of reliable, Freeman is batting .313 with 16 homers and stays squaring up everything.
- Shohei Ohtani: Even when he’s not on the mound, he changes the game with an insanely big swing.
- Andy Pages: Young and streaky, but his recent three-run homer was a sight to see, so watch for him to be aggressive early.
Betting Odds & Insights
According to FanDuel Sportsbook, here’s is where the odds sit before the first pitch:
Team | Spread | Moneyline | Total |
---|---|---|---|
Diamondbacks | +1.5 (-170) | +116 | Over 9.5 (-105) |
Dodgers | -1.5 (+140) | -136 | Under 9.5 (-115) |
Betting Trends
– The Dodgers have won 26 of their 40 games (65%), making them the favorite.
– Arizona is hitting around 47% as an underdog, which is enough to pay attention to if you like that underdog value.
– The total has gone over in 7 of the Dodgers’ last 10 games at home.
– Arizona has covered the run line in 6 of their last 8 road games.
Our Expert Analysis
We think that this game is a runs-fest waiting to happen, and here’s how we feel like it’ll go:
- The Dodgers’ lineup is absolutely stacked and averages around 6 runs per game.
- Arizona’s been streaky at the plate but can hang if they get a few barrels early.
- Pfaadt’s earlier success against the Dodgers could slow things down early on, but Knack’s volatility means Arizona will get their chances.
- Bullpens could decide this one, and L.A. probably has the better late-game arms, but only if Knack doesn’t dig himself into a hole first.
- The line total sits at 9.5, and there’s a solid argument for taking the over based on recent scoring trends and both starters’ recent form.
Best Bets
We’ve circled the two best value spots on the board, and here they are:
- Over 9.5 Total Runs (-105): Both clubs can rake, and the starting pitching matchup leans toward runs coming early and often.
- Diamondbacks Moneyline (+124): Pfaadt already stifled this Dodgers lineup once, and if he settles in early on, Arizona could pull this off before the late innings even matter.
Want to throw some skin on this one? You can check out our list of the best sports betting apps to lock in your picks for the Diamondbacks vs. Dodgers!
Wrapping It Up: What to Expect Tonight
Here’s what we’ll be watching for as the lights come up at Dodger Stadium!
- L.A. has the power and the home field, but Knack’s spot in the rotation still feels really wobbly.
- Arizona has a real shot with Pfaadt being back on the mound. He’s already proven that he can keep this Dodgers lineup off-kilter.
- We know that the batters will show up. The question is this: Will the late-inning arms show up?
- Arizona’s definitely worth a look, especially with the more dependable arm and some room to work with.

Alyssa contributes sportsbook/online casino reviews, but she also stays on top of any industry news, precisely that of the sports betting market. She’s been an avid sports bettor for many years and has experienced success in growing her bankroll by striking when the iron was hot. In particular, she loves betting on football and basketball at the professional and college levels.